Highlights

 

Nominations
 2018

International Society for Electroporation-Based Technologies and Treatments

President elect:
Luis Mir
Officers: Biological sciences:
Marie-Pierre Rols; Maja Čemažar



 

Electroporation-Based Technologies and Treatments (EBTT)
Postgraduate Course and Scientific Workshop
Ljubljana, November 10—16 2019.
13th Edition
http://2019.ebtt.org/

 

An Associated European Laboratory (LEA) is a “laboratory without walls” devoid of legal personality or capacity which brings together two or more laboratories or parts of laboratories from CNRS – and, possibly, from an higher education organization and one or more research organizations or universities from other European countries.

 

The main aim of the  LEA  EBAM  is to use an interdisciplinary approach, integrating biology, chemistry, physics, biophysics, mathematics, computational modelling and engineering, through the expertise of its members in order to

1- Enhance our understanding on the mechanisms of classical electropermeabilization and of the new nanopermeabilization (electropermea-bilization using nanosecond electric pulses), as well as on the mechanisms of transmembrane transport of molecules into electroporated cells and tissues on a microscopic and macroscopic scale.

2- Contribute to a better and safer implementation of the electropermeabilization-based applications, and to the development of new applications.

3- Develop new devices and new equipment for the nanopermeabilisation at cell and tissue levels.

4- Develop new approaches like treatment planning in existing applications, such as antitumor electrochemotherapy and in vivo gene transfer for therapeutic purposes.

5- Disseminate the knowledge and the applications in the scientific community and in the society, through publications, a one-week course (already implemented) co-directed by the LEA directors, internal and external training, and through other means that the LEA will develop and/or will apply for (to the EC programs for example).

Partners participating in the project possess complementary knowledge and skills, which only if brought together will allow for successful accomplishments of the above objectives.


Recent publications

Kotnik, L. Rems, M. Tarek and D. Miklavčič. Membrane Electroporation and Electropermeabilization: Mechanisms and Models. Annu. Rev. Biophys. 48 (2019)

Markelc B, Bellard E, Sersa G, Jesenko T, Pelofy S, Teissié J, Frangez R, Rols MP, Cemazar M, Golzio M. Increased permeability of blood vessels after reversible electroporation is facilitated by alterations in endothelial cell-to-cell junctions. J Control Release. 76:30-41 (2018)

Teissié J, Miklavcic D. Special issue on bacterial inactivation. Bioelectrochemistry. 123:260.  (2018)

Čemažar M, Serša G, Frey W, Miklavčič D, Teissié J. Recommendations and requirements for reporting on applications of electric pulse delivery for electroporation of biological samples. Bioelectrochemistry 122: 69-76 (2018)

Dermol-Černe J, Miklavčič D, Reberšek M, Mekuč P, Bardet SM, Burke R, Arnaud-Cormos D, Leveque P, O'Connor R. Plasma membrane depolarization and permeabilization due to electric pulses in cell lines of different excitability. Bioelectrochemistry 122: 103-114, (2018)

Rems L, Viano M, Kasimova MA, Miklavčič D, Tarek M. The contribution of lipid peroxidation to membrane permeability in electropermeabilization: A molecular dynamics study. Bioelectrochemistry 125: 46-57, (2019)

Pasquet L, Chabot S, Bellard E, Markelc B, Rols, M-P., Reynes J-P, Tiraby G, Couillaud F, Teissié J, Golzio M. Safe and efficient novel approach for non-invasive gene electrotransfer to skin. Scientific reports, 8: 2045-2322 (2018)

 

News

 3rd World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine, and Food & Environmental Technologies

Toulouse, September 3 –6 , 2019

 
Chair
Marie-Pierre Rols

Contact

 LEA EBAM

- Dr Lluis M. MIR, for CNRS, France,

- Pr Damijan MIKLAVCIC, for UL, Slovenia.