Highlights

Electroporation-Based Technologies and Treatments (EBTT)
Postgraduate Course and Scientific Workshop
Ljubljana, November 12—18 2017.
11th Edition
http://2017.ebtt.org/

 

Nomination
September, 2017
International Society for Electroporation-Based Technologies and Treatments
- President:                                
Damijan Miklavčič

- President elect:                         
Luis Mir
- Officer: Biological sciences
:     
Marie-Pierre Rols

 

 

Recent Publications


2017

Papers published within the scope of the LEA

Denzi, E. della Valle, F. Apollonio, M. Breton, L. M. Mir and M. Liberti. Exploring the Applicability of Nano-poration for Remote Control in Smart Drug Delivery Systems. J. Membrane Biol, 250, 31-40, 2017.

Azan, V. Untereiner, C. Gobinet, G. D. Sockalingum, M. Breton, O. Piot and L. M. Mir. Demonstration of Protein Involvement in Living Cell Electropulsation using Confocal Raman Microspectroscopy. Scientific Reports 7. 297–306, 2017.

Azan, P.J. Caspers, T.C. Bakker Schut, S. Roy, C. Boutros, C. Mateus, E. Routier, B. Besse, D. Planchard, A. Seck, N. Kamsu Kom, G. Tomasic, S. Koljenović, V. Noordhoek Hegt, A. Celebic, M. Texier, E. Lanoy, A.M.M. Eggermont, A. Paci, C. Robert, G.J. Puppels, L.M. Mir. A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents. Cancer Res. 77: 557-565, 2017

Sanz, I. Leray, A. Dewaele, D. Grébert, S. Antoine, A. Acquistapace, A Muscat, A Boukadiri and L. M. Mir. Structurally Related Odorant Ligands of the Olfactory Receptor OR51E2 Differentially Promote Metastasis Emergence and Tumor Growth. Oncotarget, 8, 4330-4341, 2017

Denzi, E. della Valle, G. Esposito, L. M. Mir, F. Apollonio and M. Liberti. Technological and Theoretical Aspects for Testing Electroporation on Liposomes. BioMed Research International, vol. 2017, Article ID 5092704, 2017

Hanna, F.M. Andre and L.M. Mir. Electrical control of calcium oscillations in mesenchymal stem cells using microsecond pulsed electric fields. Stem cell research and therapy, vol 8, art 91, 2017

D.Voyer, A. Silve, L. M. Mir, R. Scorretti and C. Poignard. Dynamic modeling of tissue electroporation. Bioelectrochemistry 119: 98-110 (2018)

Breton and L. M. Mir. Investigation of the Chemical Mechanisms Involved in the Electropulsation of Membranes at the Molecular Level. Bioelectrochemistry 119 (2018) e7966;

Azan, V. Untereiner, L. Descamps, C. Merla, C. Gobinet, M. Breton, O. Piot and L. M. Mir. Comprehensive Characterization of the Interaction between Pulsed Electric Fields and Live Cells by Confocal Raman Microspectroscopy. Analytical Chemistry 89, 10790-10797, 2017.

Hanna, A. Denzi, M. Liberti, F.M. Andre and L.M. Mir. Electropermeabilization of inner and outer membranes of cells with microsecond pulsed electric fields: Quantitative study with calcium ions. Sci. Rep. 7, art. 13079, 2017

García-Sánchez, A. Muscat, I. Leray and L. M. Mir. Pyroelectricity as a possible mechanism for cell membrane permeabilization. Bioelectrochemistry 119 (2018) 227–233;

A. Ascierto, S. Agarwala, G. Ciliberto, S. Demaria, R. Dummer, C. Duong, S. Ferrone, S. C. Formenti, C. Garbe, R. Halaban, S. Khleif, J. Luke, L. M. Mir, W. W. Overwijk, M. Postow, I. Puzanov, P. Sondel, J. M. Taube, P. T. Straten, D. F. Stroncek, J. A. Wargo, H. Zarour, and M. Thurin Future perspectives in melanoma research - “Melanoma Bridge”, Napoli, November 30th- 3rd December 2016. J. Transl. Med. 15:236-267 2017

Pillet, F., L. Gibot, M. Madi, M. P. Rols, and E. Dague. 2017. Importance of endogenous extracellular matrix in biomechanical properties of human skin model. Biofabrication 9:025017.

Tamra, A., D. Dubuc, M. P. Rols, and K. Grenier. 2017. Microwave Monitoring of Single Cell Monocytes Subjected to Electroporation. IEEE Transactions on Microwave Theory and Techniques 99:1-7.

Batista Napotnik T., Bello G., Sinner E.K., Miklavčič D. The Effect of Nanosecond, High-Voltage Electric Pulses on the Shape and Permeability of Polymersome GUVs. J Membr Biol 250: 441-453, 2017

Dermol-Černe J., Miklavčič D. From Cell to Tissue Properties – Modeling Skin Electroporation With Pore and Local Transport Region Formation. IEEE T. Biomed. Eng. PP/99: 1-11, 2017

Garcia P.A., Kos B., Rossmeisl J.H.Jr., Pavliha D., Miklavčič D.. Predictive therapeutic planning for irreversible electroporation treatment of spontaneous malignant glioma. Med Phys 44: 4968-4980, 2017

Kranjc M., Kranjc S., Bajd F., Serša G., Serša I., Miklavčič D. Predicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomography. Sci. Rep. 7: 10323: 1-10, 2017

Mahnič-Kalamiza S., Poklar Ulrih N., Vorobiev E., Miklavčič D. A comprehensive theoretical study of thermal relations in plant tissue following electroporation. Int J Heat Mass Transfer: 150-162, 2017

Novickij V., Dermol J., Grainys A., Kranjc M., Miklavčič D. Membrane permeabilization of mammalian cells using bursts of high magnetic field pulses. PeerJ 5:e3267

Burke R., Bardet S.M., Carr L., Romanenko S., Arnaud-Cormos D., Leveque P., O’Connor R.P. “Nanosecond pulsed electric fields depolarize transmembrane potential via voltage-gated K+, Ca2+ and TRP channels”. Biochimica et biophysica acta, 1859(10), pp. 2040-2050. Published: Oct. 2017

Carr L., Bardet S.M., Arnaud-Cormos D., Leveque P., O’Connor R.P., “Visualisation of an nsPEF induced calcium wave using the genetically encoded calcium indicator GCaMP in U87 human glioblastoma cells”. Bioelectrochemistry, 119C, 68-75 (2018).

Soueid M., Dobbelaar M.C.F., Bentouati S., Bardet S.M., O’Connor R.P., Bessieres D., Paillol J., Leveque P., Arnaud-Cormos D., “Delivery devices for exposure of biological cells to nanosecond pulsed electric fields”. Medical & Biological Engineering & Computing, pp.1-13. Published: 4 Jul. 2017.

Carr L., Bardet S.M., Arnaud-Cormos D., Leveque P., O’Connor R.P.“Calcium-independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells”. Scientific Report, 7, 41267. 2017. 

Kamensek U, Tesic N, Sersa G, Kos S, Cemazar M. Tailor-made fibroblast-specific and antibiotic-free interleukin 12 plasmid for gene electrotransfer mediated cancer immunotherapy. Plasmid 2017; 89: 9-15

Kos S, Vanvarenbergb K, Dolinsek T, Cemazar M, Jelenc J, Préat V, Sersa G, Vandermeulen G. Gene electrotransfer into skin using noninvasive multi-electrode array for vaccination and wound healing. Bioelectrochemistry 2017; 114: 33-41.

Savarin M, Kamensek U, Cemazar M, Heller R, Sersa G. Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response. Radiol Oncol 2017; 51: 30-9

Bosnjak M, Kamensek U, Stolfa D, Lavrencak J, Sersa G, Cemazar M. Inhibition of the innate immune receptors for foreign DNA sensing improves transfection efficiency of gene electrotransfer in melanoma B16F10 cells. J Membrane Biol 2017

Kos S, Blagus T, Cemazar M, Filipic G, Sersa G, Cvelbar U. Safety aspects of atmospheric pressure helium plasma jet operation on skin: in vivo study on mouse skin. Plos One 2017; 12(4): e0174966

Gasljevic G, Edhemovic I, Cemazar M, Brecelj E, Gadzijev EM, Music MM, Sersa G. Histopathological findings in colorectal liver metastases after electrochemotherapy. Plos One 2017; 12(7): e0180709

Kranjc M, Kranjc S, Bajd F, Sersa I, Sersa G. Miklavcic D. Predicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomography. Sci Rep 2017; 7(1): 10323

Salvadori C, Svara T, Rocchigiani G, Millanta F, Pavlin D, Cemazar M, Lampreht Tratar U, Sersa G, Tozon N, Poli A. Effects of electrochemotherapy with cisplatin and peritumoral IL-12 gene electrotransfer on canine mast cell tumors: a histopathologic and immunohistochemical study. Radiol Oncol 2017; 51: 286-94. 2017

Ursic K, Kos S, Kamensek U, Cemazar M, Scancar J, Bucek S, Kranjc S, Staresinic B, Sersa G. Comparable effectiveness and immunomodulatory actions of oxaliplatin and cisplatin in electrochemotherapy of murine melanoma. Bioelectrochemistry 2017; 119: 161-171.

 


 

Recent publications

Azan, V. Untereiner, C. Gobinet, G. D. Sockalingum, M. Breton, O. Piot and L. M. Mir. Demonstration of Protein Involvement in Living Cell Electropulsation using Confocal Raman Microspectroscopy. Sci Rep  7. 297–306, (2017)

Pillet, F., L. Gibot, M. Madi, M. P. Rols, and E. Dague. Importance of endogenous extracellular matrix in biomechanical properties of human skin model. Biofabrication 9:025017 (2017)

Kranjc M., Kranjc S., Bajd F., Serša G., Serša I., Miklavčič D. Predicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomography. Sci Rep 7: 10323: 1-10, (2017)

Carr L., Bardet S.M., Arnaud-Cormos D., Leveque P., O’Connor R.P.“Calcium-independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells”. Sci Rep  7, 41267. (2017)

Kos S, Blagus T, Cemazar M, Filipic G, Sersa G, Cvelbar U. Safety aspects of atmospheric pressure helium plasma jet operation on skin: in vivo study on mouse skin. Plos One ; 12: e0174966 (2017)

Gasljevic G, Edhemovic I, Cemazar M, Brecelj E, Gadzijev EM, Music MM, Sersa G. Histopathological findings in colorectal liver metastases after electrochemotherapy. Plos One 12: e0180709 (2017)

Kranjc M, Kranjc S, Bajd F, Sersa I, Sersa G. Miklavcic D. Predicting irreversible electroporation-induced tissue damage by means of magnetic resonance electrical impedance tomography. Sci Rep  7: 10323 (2017)

News

24thInternational Symposium on Bioelectrochemistryand Bioenergetics of the BioelectrochemicalSociety
Lyon, July 3 –7, 2017
http://www.bes2017.fr/
(NEXT LEA EBAM MEETING)

2ndWorld Congress on Electroporation and Pulsed Electric Fields
Norfolk, September 24 –28, 2017
http://wc2017.electroporation.net

Contact

 LEA EBAM

- Dr Lluis M. MIR, for CNRS, France,

- Pr Damijan MIKLAVCIC, for UL, Slovenia.